His primary research interests include microbial diversity at pesticide polluted sites, genetic and biochemistry of hexachlorocyclohexane (HCH) degradation and development of HCH bioremediation technology.
Prof. Rup Lal is also interested in the evolution of lin genes and genetic manipulation of rifamycin producer Amycolatopsis mediterranei. His group has already sequenced genomes of Amycolatopsis mediterranei S699, Thermus sp. RL, Acinetobacter sp. HA and Sphingobium indicum B90A. He has also explored metagenomics diversity of the HCH dumpsite and currently working on the metagenomic revelations of the hot water springs (with temp. of ~96 degrees Celcius) situated atop the Himalayan ranges at Manikaran, Himachal Pradesh.